Dr Maja Simić - Plastična hirurgija 1
Dr Maja Simić - Plastična hirurgija 2
Dr Maja Simić - Plastična hirurgija 3
(+381) 60 4800 499
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Microneedling and Mesotherapy — Deep Stimulation and Skin Renewal

Modern aesthetics increasingly favours treatments that activate the skin's natural processes, rather than merely "filling" or "masking" concerns.

Microneedling and mesotherapy represent a combined approach that improves skin texture, tone and quality, delivering long-lasting and natural results.


What is microneedling?

Microneedling (dermapen) uses fine, controlled micro-needles that create microchannels in the skin, activating the natural regeneration process and stimulating collagen and elastin.

This treatment improves:

  • Skin texture and evenness of complexion
  • Reduction of fine lines and scars
  • Skin firmness and elasticity

What is mesotherapy?

Mesotherapy involves microinjection of active substances — hyaluronic acid, vitamins, minerals and peptides — directly into the superficial layers of the skin.

The result is intensive hydration, restoration of tone and stimulation of natural regenerative processes.


When is the combination of microneedling and mesotherapy recommended?

This synergy of treatments is ideal for individuals who wish to achieve:

  • Natural refreshment of the skin of the face, neck, décolletage or hands
  • Reduction of fine lines and wrinkles
  • Improvement of tone, texture and radiance
  • Regeneration of skin damaged by sun exposure, stress or acne

What does the treatment involve?

Following consultation and skin analysis, the treatment begins with microneedling using a dermapen to activate renewal processes,
after which active substances from mesotherapy cocktails are applied into the microchannels.

The procedure takes approximately 30–45 minutes and is performed with topical anaesthetic cream for maximum comfort.

Mild redness and a sensation of skin tightness may occur for several hours after treatment, which is entirely normal and resolves within 24–48 hours.


Results and duration of effect

Results are visible after the first treatment — the skin appears refreshed, smoother and hydrated.

For optimal effect, a series of 3–4 treatments spaced 3–4 weeks apart is recommended, followed by maintenance 1–2 times per year.

The effect is cumulative — the skin becomes firmer, more elastic and more radiant.


💬 Philosophy of treatment:
"Microneedling and mesotherapy don't change the skin, they return it to its best state — healthy, radiant and vital. When the skin functions from within, its appearance becomes naturally beautiful and long-lasting."